Endocrine Abstracts

Cranial diabetes insipidus (CDI) is commonly idiopathic but can also be due to tumours of the pituitary & hypothalamus or surgery to remove these tumours. It can also occur due to infiltrative processes including metastatic malignancy. Pituitary metastases are not a common clinical entity although it can be a common finding in autopsy in advanced cancer when the pituitary & the sella have been evaluated. In this abstract, I will discuss two cases of CDI as a presentati...

Introduction: Copeptin is the C-terminal fragment of proAVP and provides an alternative measure of AVP secretion. While direct measurement of AVP during hypertonic saline infusion has been recommended as a diagnostic test for diabetes insipidus (DI), the number of reports examining the utility of copeptin in this context is limited. Here we describe a series of cases where measurement of copeptin during saline infusion has contributed to ...

Introduction: Copeptin is the C-terminal fragment of proAVP and provides an alternative measure of AVP secretion. While direct measurement of AVP during hypertonic saline infusion has been recommended as a diagnostic test for diabetes insipidus (DI), the number of reports examining the utility of copeptin in this context is limited. Here we describe a series of cases where measurement of copeptin during saline infusion has contributed to ...